As we age, our NAD levels drop, leading to a decline in these functions. Not surprisingly, this contributes to the aging process. This is why people are trying to maintain or boost their NAD levels. Experts believe maintaining higher levels of NAD can potentially slow down aging and promote longevity. (18)

One of the ways to increase NAD levels is with NMN supplements. Nicotinamide mononucleotide (NMN) is a precursor to NAD, meaning it’s a substance that the body can convert into NAD. It’s like a raw material that cells can use to create more of the NAD ‘currency’ they need to function optimally.

With two decades of experience as a personal trainer and fitness nutrition specialist, I’ve witnessed a shift in client inquiries from how to get six-pack abs to a desire for longevity and improved quality of life. People don’t just want to live longer; they want to feel better too. While exercise and diet are important, NMN supplements offer a promising way to naturally boost NAD levels. For my review, I tested several options to help you find the best NMN supplement.

Medical disclaimer: This article is intended for educational and informational purposes only. It is not intended as a substitute for medical advice. For health advice, contact a licensed healthcare provider.

How We Chose the Best NMN Supplements

I’d argue that choosing the best NMN supplement is more difficult than most other supplements because it hasn’t been on the market for very long. With limited time for rigorous scrutiny, finding products that truly align with the science can be a challenge.

Here at Breaking Muscle, there are several factors that we consider to ensure you get the best NMN supplements for your budget and lifestyle.

Science-Based Formulas

We give priority to products featuring ingredients backed by proven scientific evidence. 

Ingredients such as NMN, resveratrol, and vitamin D have consistently demonstrated anti-aging benefits in studies. (5)(8) (14)

What’s more, we evaluate the dosage of each ingredient, aiming to closely align it with the quantities shown in these studies for maximum effectiveness.

Third-Party Verification

Let’s face it: Supplements that undergo third-party testing instill greater confidence. 

We’ve favored products that have been through legitimate testing by independent laboratories, assuring purity and potency.

Real-World User Feedback

Real-life experiences offer invaluable insights. We’ve conducted a thorough review of user feedback, meticulously examining reports of effectiveness, benefits, and any potential drawbacks to provide you with a comprehensive assessment.

Company Reputation

The track record of a brand matters. We’ve chosen companies with a reputation for integrity, transparency, and a commitment to customer satisfaction.

Balancing Value

Our aim is to recommend supplements that strike the right balance between cost and effectiveness, ensuring you receive the best value for your investment.

Safety

Above all, your well-being is our top concern. We’ve focused on supplements that incorporate proven, safe ingredients without unnecessary additives or fillers. 

Naturally, products associated with a long history of adverse effects have been excluded from our list.

Our Top Picks for the Best NMN Supplement

• Best NMN Supplement Overall: Lifeforce Peak NMN
• Best Anti-Aging NMN Supplement: Wonderfeel Youngr NMN
• Best NMN and Resveratrol Supplement: Omre NMN + Resveratrol
• Best Budget NMN Supplement: Genuine Purity Liposomal NMN+
• Best Pure NMN Supplement: partiQlar Pure NMN

Best NMN Supplement Overall: Lifeforce Peak NMN

Lifeforce Peak NMN

4.5

• Daily dose: Three capsules
• Cost per serving: One-time purchase: $3.00 per serving / Monthly subscription: $2.33 per serving
• NMN per serving: 375 milligrams
• Key ingredients: Nicotinamide mononucleotide, berberine HCl, white mulberry extract, spermidine, lithium
• Third-party testing: No

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I’ve been a big fan of Lifeforce since I tried the brand in my search for the best testosterone booster. Once again, they didn’t disappoint. In fact, the team and I were so impressed with Peak NMN that we assigned it as our best NMN supplement overall.

What clinched it for us? 

A combination of science-backed ingredients at doses that work, all without breaking the bank. Plus, Peak NMN targets something special: it not only supports long-term cellular health but also takes on blood sugar — a key factor in aging. Consistently elevated blood sugar can damage mitochondria or cellular ‘powerhouses’ and contribute to age-related diseases. (1)

Lifeforce tackles this with two key ingredients: Berberine HCl (660 milligrams) and White Mulberry Extract (200 milligrams), both proven to support healthy blood sugar levels. It also includes spermidine, which helps with cellular growth and renewal. It’s known for aiding in autophagy, the body’s way of cleaning out old cellular junk to make way for new, healthier cells. (2)(3)(4)

Naturally, Lifeforce’s star ingredient is NMN, which has been shown to boost NAD levels, helping to keep your cells strong. NAD plays a significant role in all cellular processes, most notably, energy production, DNA repair, and the regulation of cellular aging. (5)

For me, one of the features of Peak NMN that stands out from other NMN supplements is its quality and stability. It contains HPLC-tested NMN boasting 99 percent purity and a 24-month shelf life. 

Not only are you getting the highest quality form of NMN but it’s also going to last much longer than most other NMN supplements. For context, most brands of NMN have a three-month shelf life when stored at room temperature. To get around this, simply put your NMN supplement in the refrigerator.

Finally, one of my favorite features of Lifeforce supplements is the option to add a specialized home blood test that evaluates dozens of biomarkers focusing on aging and longevity. This test, supported by telehealth consultations and individualized guidance from a healthcare professional, aims to provide insights into biological age, cellular health, and factors influencing lifespan. Taking these tests before and several months after consistently using the supplement (and following the advice of the telehealth experts) can showcase how your cellular health is improving.

One of the team members at Breaking Muscle went through this Lifeforce Diagnostics test, and he was amazed at the professionalism of the team as well as the preciseness and quality of the information he received from it. He especially liked the convenience factor of having a phlebotomist come to the location of his choice. It’s very easy to schedule and the whole process takes less than 10 minutes from the comfort of your home.

Why didn’t Peak NMN get a perfect score? My only gripe with the supplement is the dosage of NMN. Sure, it provides 375 milligrams per serving, which may be enough if you’re new to NMN and want to avoid potential side effects like digestive issues and skin irritation. But what happens when your body adjusts, and you want to take a dosage closer to 1,000 milligrams (the higher end of the recommended daily dose)? 

Compare the 375 milligrams of NMN in Peak NMN to the 900 milligram serving in Wonderfeel Youngr NMN – A huge difference. If you want to get close to this when taking Peak NMN, you’ll have to either double the dose or take a separate NMN supplement. If you choose the latter, I’d recommend going with our choice for the best budget NMN supplement, Genuine Purity Liposomal NMN+, to save some cash.

Best Anti-Aging NMN Supplement: Wonderfeel Youngr NMN

Wonderfeel Youngr NMN

4.5

• Daily dose: Two capsules
• Cost per serving: Introductory monthly subscription: $2.43 per serving / Regular monthly subscription: $2.76 per serving / One-time purchase: $2.93 per serving
• NMN per serving: 900 milligrams
• Key ingredients: Nicotinamide mononucleotide, vitamin D3, trans-resveratrol, olive fruit extract, ergothioneine
• Third-party testing: Yes

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On a list of NMN supplements all claiming to reduce the impacts of aging, how does one stand above the rest as the best anti-aging NMN supplement?

For us, it’s all about a multi-targeted approach to fight the signs of aging. In other words, we want to see a supplement with multiple ingredients known for longevity benefits. And that’s what sets Wonderfeel Youngr NMN apart from the rest.

NMN is one of several anti-aging ingredients in Wonderfeel Youngr NMN. Let’s break down the ingredient list, starting from the top with vitamin D3. This is one of my favorite vitamins and one that I believe most people are lacking in.

Vitamin D3 is often associated with bone health, but it does so much more than that. When it comes to anti-aging benefits, vitamin D3 enhances immune function, supports cardiovascular health, and staves off cognitive decline. (14)

For men, vitamin D3 is especially important for hormonal health as it acts as a building block for testosterone. Low levels of testosterone are associated with weight gain, muscle loss, mood swings, and fatigue – All things that are pro-aging. (15)

Most importantly for our purposes, vitamin D3 is particularly useful because it seems to help stop the build-up of certain proteins that are commonly found in older people. Also, taking extra vitamin D3 may help reduce signs of aging at the cellular level, which suggests it might help to slow down how quickly we age biologically. (14)

There is one issue with the inclusion of vitamin D3 and it’s the exclusion of vitamin K2. When you take supplements, you want to try to pair or group ingredients that have a synergistic effect. In this case, vitamin K2 improves the bioavailability of vitamin D3. I’m not saying your body won’t see any benefit from the vitamin D3 in Wonderfeel Youngr NMN, but some level of bioavailability and potential benefit could be lacking thanks to the absence of vitamin K2.

NMN is the next ingredient on the list. What I love about Wonderfeel Youngr NMN is that it provides a dosage level that’s on the higher side at 900 milligrams per serving. As mentioned above, this is close to what David Sinclair takes on a daily basis.

Next up, we have trans-resveratrol. Again, this is another homerun ingredient. Trans-resveratrol is better than traditional resveratrol because it is the more bioavailable and biologically active form of the compound. While it is the preferred form of resveratrol, it is lacking in dosage at only 100 milligrams per serving. For reference, the standard dosage starts at 250 milligrams.

The next ingredient is olive fruit extract, which contains hydroxytyrosol, a powerful antioxidant that supports cardiovascular health by promoting healthy cholesterol levels and blood flow (circulation). It also has a lot of polyphenols and these compounds offer protective effects against oxidative stress—a key factor in aging—and inflammation, contributing to overall longevity. (16)

Finally, the ingredient list caps off with a super antioxidant known as ergothioneine, offering benefits for anti-aging, vascular health, and neuroprotection. It combats oxidative stress and inflammation, which reduces age-related cellular damage. It’s also thought to preserve telomeres, the chromosome endcaps that typically shorten with age. (17)

Cementing its place as the best anti-aging NMN supplement, is there anything that could make this supplement better? 

You bet! It is the first supplement on our list that focuses on earth-friendly packaging. Your first order will arrive in a durable and refillable glass bottle. After that, you’ll receive your supplement in completely recyclable and biodegradable pouches. Simply refill the glass bottle and recycle the pouch. Even if the pouch winds up in the garbage, it will break down within six to 42 months, leaving behind no trace of microplastics.

Do something positive for yourself while doing something productive for the environment.

Best NMN and Resveratrol Supplement: Omre NMN + Resveratrol

Omre NMN + Resveratrol

4.5

• Daily dose: Two capsules
• Cost per serving: One-time purchase: $1.99 per serving / Monthly subscription: $1.89 per serving
• NMN per serving: 500 milligrams
• Key ingredients: NMN powder, resveratrol, BioPerine 
• Third-party testing: Yes

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When the longevity trend started, the abbreviations “NMN” and “NAD” were virtually unheard of. Instead, everyone was talking about resveratrol. Just because NMN is now taking center stage within the cellular health and longevity movement doesn’t mean resveratrol is obsolete. In fact, we recommend taking them both together. And that’s why our pick for the best NMN and resveratrol supplement is Omre NMN + Resveratrol.

What exactly is resveratrol?

A type of antioxidant known as a polyphenol, resveratrol is found in the skin of red grapes and berries as well as cocoa. Antioxidants fight against oxidative stress in your body, which is caused by an excess of free radicals. These are molecules that can damage cells and they are linked to several chronic diseases along with aging.

And this is where resveratrol comes in as an all-around longevity supplement. 

From a cardiovascular standpoint, resveratrol has been shown to support heart health by improving blood flow and reducing inflammation. Some research even suggests it can support healthy blood sugar levels. (Remember what we said above about blood sugar levels and aging?) (6)(7)

For our purposes, the most important benefits of resveratrol are its anti-aging properties, which include:

• DNA repair: Activates proteins called sirtuins, aiding in DNA repair and cellular health. (8)
• Antioxidant properties: Protects cells against oxidative stress, which contributes to aging. (9)
• Cognitive protection: Offers neuroprotective effects that may slow neurodegenerative diseases. (10)
• Cellular health: Improves mitochondrial function, leading to increased energy production and cellular vitality. (11)

Combining resveratrol with NMN may offer synergistic benefits. Most notably, the antioxidant activity of resveratrol complements the role of NMN in supporting mitochondrial (cellular) function.

I love the idea of combining two longevity heavy hitters. This is something you don’t see in many NMN supplements. And the fact that Omre uses trans-resveratrol earns it extra points. Why? Trans-resveratrol is the more bioavailable form of resveratrol meaning your body can properly ingest and assimilate the ingredient.

What’s more, both ingredients are dosed at 500 milligrams per serving, well within the same range used in studies and research. If you are interested in gradually building up to a higher dose, you can simply double your dose and you’ll be within the same range as longevity expert, David Sinclair.

Best Budget NMN Supplement: Genuine Purity Liposomal NMN+

Genuine Purity Liposomal NMN+

3.5

• Daily dose: One capsule
• Cost per serving: Annual: $0.49 per serving / Semi-annual: $0.55 per serving / One-time purchase: $1.17 per serving
• NMN per serving: 250 milligrams
• Key ingredients: Nicotinamide mononucleotide
• Third-party testing: No

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If there’s one thing that you’ll quickly notice about NMN supplements, it’s the price tag. The sticker shock is going to naturally lead to the question of whether the best budget NMN supplement exists and if it’s worth buying. Thankfully, that can be answered with a double “yes.”

Introducing Genuine Purity Liposomal NMN+.

There are three major differences between Genuine Purity NMN and the rest of the options on this list: price, dosage, and bioavailability.

Let’s start with the obvious one: price. Even if you purchase a single bottle of Genuine Purity, you’re only paying $1.17 per serving, which is half of what some of the other brands are charging. If you want an insanely good deal for inexpensive supplements, you can’t beat buying one year’s worth upfront.

But there’s a reason for the lower price point and it has to do with ingredients and dosage. The only ingredient you’ll find in Genuine Purity is NMN. So, if you want those other ingredients that support longevity and cellular health, you’ll have to buy them separately and build your own stack. This is something I highly recommend. Not only can it be more cost-effective, but you’re guaranteed to get the proper dosage.

Speaking of dosages, you’ll see that it’s on the lower end of what the major studies used. Most of the studies mentioned above used anywhere from 250 milligrams to 1,250 milligrams. Genuine Purity provides 250 milligrams of NMN, which is among the lowest on our list. It isn’t bad if you’re just starting out and you want to see how your body responds to NMN, but for the long term, you’ll need to double or triple the dosage. 

Here’s the thing about that: At this price point, that’s still a good deal! If you buy a year upfront, you can easily triple your dosage and it’ll still end up being cheaper than most of the other NMN supplements out there.

Finally, let’s talk about bioavailability, which might be a double-edged sword for Genuine Purity. On one hand, it uses liposomal delivery technology, which can significantly enhance the absorption of NMN into the bloodstream. Liposomal delivery means that the NMN is encased in a sort of protective bubble made from lipids (fats). As a result, the NMN can bypass the harsh acids in the digestive system and get delivered directly into the cells where it’s needed most. (12)

On the other hand, not all liposomal products are created equal. The quality and size of the liposomes, as well as the stability of the liposomal structure, can greatly affect the uptake of NMN. Luckily, Genuine Purity claims to use high-quality liposomal encapsulation to ensure that you’re getting the most out of each serving.

One final point about bioavailability involves the shelf stability of the product. NMN supplements are notorious for having a poor shelf life. Yes, brands do spend the extra cash to ensure a longer shelf life like Lifeforce: Peak NMN. However, Genuine Purity doesn’t mention anything about an extended shelf life. As I mentioned above, if your aim is to take double or triple the serving size, shelf life isn’t something you’ll need to worry about.

Best Pure NMN Supplement: partiQlar Pure NMN

partiQlar Pure NMN

4.0

• Daily dose: One capsule
• Cost per serving: Annual: $0.71 per serving / Semi-annual: $0.90 per serving / One-time purchase: $1.20 per serving
• NMN per serving: 500 milligrams
• Key ingredients: Nicotinamide mononucleotide
• Third-party testing: Yes

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It should come as no surprise that the quality of supplements can range drastically. Take protein supplements as an example. If you buy whey protein concentrate, you might be getting a product that’s only 60% protein. If you buy whey protein isolate, you’ll get a hyper-filtered product that can deliver over 99% protein per serving. Both are protein supplements, but one is vastly superior to the other in terms of purity.

And the same goes for NMN supplements.

Purity or how much NMN you’re getting in every serving can vary wildly depending on the brand. On our list, we made sure to find products that had no less than 96% purity, which is the minimum you should always look for when shopping for an NMN supplement. With a product that pure, does it really matter which one you choose? 

Absolutely. Those last few purity points can really make a difference especially if it’s paired with a bioavailability delivery system ensuring optimal uptake.

When it comes to the best pure NMN supplement, partiQlar Pure NMN gets our vote for three reasons: a pure product, a knack for transparency, and an awesome team.

partiQlar’s NMN boasts an industry-leading purity that exceeds 99% and that’s a huge deal. This isn’t just some marketing ploy, it’s a claim that’s backed up by independent third-party laboratory testing. If you visit the official website, you’ll see that all the test results are right there on the homepage. (13)

Aside from the absurdly high purity of partiQlar’s NMN, one of the factors that I noticed is how transparent they are about the team behind the product. Not only is this pretty uncommon for NMN supplements, but you’d be hard-pressed to find this transparency with any supplement.

Knowing who is making your product means you can become a Google investigator and do your research for your own peace of mind (and to appease your supplement OCD). Very long story short: partiQlar sources their NMN from Effepharm. According to the official website, they are supposedly renowned for their research and development team of U.S. specialists along with their rigorous testing process.

Continuing with the idea of transparency and testing, partiQlar upholds rigorous standards to align with USP (United States Pharmacopeia) quality benchmarks. Also, the production facilities responsible for crafting partiQlar’s NMN are recognized by the National Sanitation Foundation (NSF) and Underwriters Laboratories (UL), reflecting adherence to the stringent Good Manufacturing Practice (GMP) guidelines.

Now, with that said, adhering to GMP guidelines is commonplace even if a supplement doesn’t specifically mention it on their website. Supplement manufacturers in the United States must adhere to GMP standards in order to operate. So, while it’s not exactly unique, it is nice to know that your supplements are in good hands.

In short, with an elite team, production facilities, and third-party testing, partiQlar is serious about the purity and effectiveness of its NMN.

What Is NMN?

Aside from being almost impossible to pronounce correctly on the first try, nicotinamide adenine dinucleotide (NAD) has an essential role in all cellular functions. 

The catch is that NAD levels naturally decline as you get older. This can lead to a variety of age-related health issues like slowing metabolism and cellular dysfunction. In a vicious cycle, the less NAD you have, the worse these issues get and the faster you age.

Enter nicotinamide mononucleotide, or NMN, a precursor to NAD. 

Put simply, NMN is what your body uses to make more NAD. Recent studies and praise from longevity experts like David Sinclair have sparked interest in NMN supplements to naturally boost NAD levels. 

The goal? To fight back against age-related decline in cellular health while improving overall longevity.

Benefits of Taking NMN

As a precursor to NAD, research suggests several potential health benefits associated with NMN supplementation:

Anti-Aging and Longevity 

NMN has exhibited numerous potential benefits against aging in different animal studies, including better metabolism and protection against diseases that come with age. Research suggests it may boost energy management within the body and enhance the body’s response to insulin as well as overall blood fat levels. (19)

Increased Energy Metabolism and Physical Activity

Supplementation with NMN has been suggested to improve energy expenditure and physical activity. A study indicated that NMN supplementation enhances neuronal function and physical activity, suggesting it may prevent the decline in energy metabolism associated with aging​​. (20)

Enhanced Physical Endurance and Metabolism

Continuing with the point above, research has found that NMN supplementation can improve endurance capacity, particularly in amateur runners, by enhancing oxygen delivery to muscle tissue and bringing energy to cells that are depleted during exercise​​. (20)

Cognitive and Cardiovascular Health

NMN supplementation has been linked to improved neuronal function in the brain and is suggested to have preventive and therapeutic potential in vascular cognitive impairment. (21)

How Long Does It Take for NMN to Start Working?

The one thing that I can’t stress enough is that NMN supplements are not like your favorite pre-workout supplements. You’re not going to feel them kick in with a bang after 20 minutes.

While several prominent biohackers suggest that you can use NMN as a nootropic (cognitive focus) supplement, I don’t agree with this. I believe the idea with NMN supplements is to promote improved cognitive function over the long term.

Besides, most nootropic-focused NMN supplements also contain other fast-acting ingredients that you’ll feel right away like caffeine and theobromine. Be sure not to confuse longevity supplements with nootropics.

It’s important to keep in mind that NMN is a long-term investment in your cellular health and overall longevity. So, don’t get discouraged if you don’t see immediate results. Stay consistent with your NMN supplement. The best way to determine if NMN is working for you is to take a biological age test once every several months and compare the differences. As mentioned above, we highly recommend Lifeforce Diagnostic, which measures more than 40 biomarkers and includes a personalized plan to optimize your health.

What Is the Best Way to Take NMN?

Hands down, the gold standard of absorption is intravenous. If you have the money and the time, you can find NAD drips at your local health spa. The results are immediate with many people citing a difference in how they feel the same day and throughout the week. The catch? NAD drips are notorious for making you nauseous. They are also extremely pricey. 

The simpler and more affordable way is with the NMN supplement.

NMN can be a bit finicky when it comes to how it’s best absorbed. The consensus is that sublingual (under the tongue) absorption is the way to go. This method allows NMN to bypass your digestive system and head straight into your bloodstream for faster results.

How Much NMN Should I Take Per Day?

This really depends on how comfortable you are with taking a “David Sinclair dose.” Some people jump right into taking 1,000 milligrams per day. 

But if you want to play it safe, many beginners start with around 250 milligrams to 500 milligrams per day. This is a good baseline to see how your body responds. As you continue to take the NMN supplement, you can gradually increase the dosage, but only if it makes sense for your goals and budget. 

What To Consider When Looking for an NMN Supplement

When shopping for an NMN supplement, here are some of the key factors to keep in mind:

Your Goals

When looking for an NMN supplement, I suggest asking yourself, “What do I want to accomplish by taking this?” 

• Do you want to support long-term longevity in your body and brain? 
• Are you looking to lower your biological (cellular) age?
• Or are you looking for something fast-acting that can help you focus?

If the first two goals sound like what you’re after, then an NMN supplement can be a great complement to a healthy diet and exercise program.

If you’re more interested in that third goal, an NMN supplement isn’t going to give you what you’re after. As I mentioned above, although NMN is sometimes marketed as a nootropic, it’s not going to give you a feeling comparable to caffeine. Only stimulants will do that and NMN is not a stimulant.

So, before you buy an NMN supplement, make sure it aligns with what you’re trying to accomplish in your health journey.

Recommended Dosage

The typical dosage for NMN supplements ranges between 250 milligrams and 1,250 milligrams. 

Should you start with a lower dosage? That really depends on your comfort level. 

Plenty of people jump right into taking 1,000 milligrams per day without any issues. If you’re someone who is new to NMN or supplements in general, consider starting out with 250 milligrams. If your body responds well to this dosage for a few weeks, gradually increase it. You can do that by simply doubling the serving that you’re currently taking.

With all that said, always consider speaking with a healthcare provider to help tailor your choice of the proper dosage based on your medical history and goals.

Ingredients and Ingredient Quality

You know you want to take an NMN supplement and you’re confident about the dosage. Now it’s time to make sure you’re getting quality ingredients. 

Here are several factors to look for when buying an NMN supplement:

• Purity: Buy an NMN supplement that contains at least 96 percent purity.
• Third-party testing: Look for products that have been third-party tested for quality assurance.
• Certifications: Certifications such as GMP or NSF signify a product’s high-quality manufacturing.
• Complementary ingredients: Check that added ingredients enhance efficacy and offer additional health benefits.
• Additives and fillers: Avoid supplements with unnecessary additives, fillers, or any low-quality ingredients.
• Product reviews and company reputation: Research the manufacturer’s reputation and read customer reviews to gauge the effectiveness and reliability of the product.

Safety

NMN supplements shouldn’t be a gamble. You should be able to confidently take your choice of supplement without worrying about your safety. 

Here are some tips to keep yourself safe when shopping for NMN supplements:

• Check for interactions with medications. If you are currently taking medication, it’s crucial to understand how NMN might interact with those medications. Consult with a healthcare provider to ensure there are no potential negative interactions.
• Ensure the supplement is backed by clinical research. Look for supplements that have been supported by clinical research. While research on NMN is still emerging, some products may have more scientific backing than others.
• Ensure the brand adheres to safe manufacturing standards. Check to see if the supplement is produced in facilities that follow high safety standards, such as GMP-certified facilities. This ensures that the product is made with a high degree of consistency and control.

Potential Side Effects

NMN supplements are usually very safe and easy to handle. Still, some side effects have been reported, including the following:

• Digestive issues such as nausea, vomiting, diarrhea, and abdominal pain
• Gastrointestinal discomfort, including bloating and indigestion
• Skin irritation and allergic reactions
• Flushing and headaches

If you experience any of these, reducing the dosage or discontinuing use may be necessary. Either way, I’d recommend speaking with your doctor. Also, be sure to check the ingredient label to ensure the side effects are coming from the NMN and not another ingredient.

If you’re concerned about the potential side effects of NMN supplements, start with a lower dosage like 250 milligrams, and gradually increase it to gauge your body’s tolerance. Keep a close watch on your body’s reactions after starting NMN supplementation. Any new or unexpected symptoms should be taken seriously and discussed with a healthcare provider.

How To Get the Best Results from an NMN Supplement

There’s more to throwing a supplement capsule in your mouth and going about your day. If you want to get the most from your NMN supplement, here are several tips to consider:

Be Consistent

Above all, if you want to see results, you need to be consistent with taking your supplement. When taken at the same time each day, NMN supplements can help maintain stable levels of NAD in the body. 

In addition to consistency, the timing of your NMN dose might play a role in its efficacy. (And I stress the word “might.”)

There’s some evidence to suggest that taking NMN in the morning could align with your body’s natural rhythms for producing NAD. 

On the other hand, I’ve read that some experts recommend taking NMN at night to help with sleep. 

Does it matter? Overall, I’d recommend finding a time that works best for you and sticking with it. Better to be consistent with taking the supplement than trying to time it perfectly amidst a chaotic schedule and missing doses.

Remember That Diet and Exercise Come First 

Don’t forget, supplements are just part of the equation. As I always say to my clients, “Supplements are supplemental.” They should never be the star of the show – That privilege belongs to diet and exercise.

Eating right and staying active are essential if you want to see the best results. Before considering supplements, I’d suggest reviewing your current fitness and meal plan. Could they use some work? If so, then focus your time, energy, and money on those first.

Once your foundations with food and fitness are solid, then you can bring supplements into the mix.

Consider Synergistic Supplements

Assuming your diet and exercise program are all taken care of, you can look at longevity supplements beyond NMN.

While incredible on its own, NMN can be part of a broader supplement strategy. For example, combining NMN with resveratrol, a compound that also supports cellular health, may enhance the effects of NMN.

This isn’t a requirement but something to consider if your goal is to optimize anti-aging benefits and longevity.

Monitoring Progress and Adjust

Finally, I’d recommend keeping track of how you feel before and after starting the NMN supplement. Use the notepad on your phone and track any changes in energy levels, cognitive function, and overall wellness to gauge the supplement’s effectiveness.

Outside of noting how you feel, if you’re serious about tracking your results, I’d suggest a biomarkers panel test like the one Lifeforce offers. Doing this every quarter or every six months will give you the best idea of how you’re progressing and the changes you might need to make, especially if you’re chatting with a longevity expert.

Final Thoughts

I’m glad that longevity is finally a big focus in the industry. I’m ecstatic when clients ask me questions about living a longer life AND feeling better during those extended years.

Most importantly, I believe that NMN supplements have the potential to play an important role in achieving those anti-aging goals.

However, I’m still a big believer in the basics. 

There’s no “magic pill” that’s going to keep you young forever — at least, not yet there isn’t. Until that day arrives, I can’t stress this enough: Focus on mastering your nutritional choices, get consistent with an exercise program, and consider mental health exercises like meditation so you can live a well-balanced, healthy life. Once these are in order, you can complement your lifestyle with NMN supplements.

Best NMN Supplement: Side-by-Side Comparison

Best NMN Supplement Overall	Best NMN and Resveratrol Supplement	Best Budget NMN Supplement	Best Pure NMN Supplement	Best Anti-Aging NMN Supplement
Lifeforce Peak NMN	Omre NMN + Resveratrol	Genuine Purity Liposomal NMN+	partiQlar Pure NMN	Wonderfeel Youngr NMN
Primary Rating: 4.5	Primary Rating: 4.5	Primary Rating: 3.5	Primary Rating: 4.0	Primary Rating: 4.5
Description: Daily dose: Three capsules Cost per serving: One-time purchase: $3.00 per serving / Monthly subscription: $2.33 per serving NMN per serving: 375 milligrams Key ingredients: Nicotinamide mononucleotide, berberine HCl, white mulberry extract, spermidine, lithium Third-party testing: No	Description: Daily dose: Two capsules Cost per serving: One-time purchase: $1.99 per serving / Monthly subscription: $1.89 per serving NMN per serving: 500 milligrams Key ingredients: NMN powder, resveratrol, BioPerine  Third-party testing: Yes	Description: Daily dose: One capsule Cost per serving: Annual: $0.49 per serving / Semi-annual: $0.55 per serving / One-time purchase: $1.17 per serving NMN per serving: 250 milligrams Key ingredients: Nicotinamide mononucleotide Third-party testing: No	Description: Daily dose: One capsule Cost per serving: Annual: $0.71 per serving / Semi-annual: $0.90 per serving / One-time purchase: $1.20 per serving NMN per serving: 500 milligrams Key ingredients: Nicotinamide mononucleotide Third-party testing: Yes	Description: Daily dose: Two capsules Cost per serving: Introductory monthly subscription: $2.43 per serving / Regular monthly subscription: $2.76 per serving / One-time purchase: $2.93 per serving NMN per serving: 900 milligrams Key ingredients: Nicotinamide mononucleotide, vitamin D3, trans-resveratrol, olive fruit extract, ergothioneine Third-party testing: Yes
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Best NMN Supplement Overall

Lifeforce Peak NMN

Primary Rating:

4.5

Description:

• Daily dose: Three capsules
• Cost per serving: One-time purchase: $3.00 per serving / Monthly subscription: $2.33 per serving
• NMN per serving: 375 milligrams
• Key ingredients: Nicotinamide mononucleotide, berberine HCl, white mulberry extract, spermidine, lithium
• Third-party testing: No

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Best NMN and Resveratrol Supplement

Omre NMN + Resveratrol

Primary Rating:

4.5

Description:

• Daily dose: Two capsules
• Cost per serving: One-time purchase: $1.99 per serving / Monthly subscription: $1.89 per serving
• NMN per serving: 500 milligrams
• Key ingredients: NMN powder, resveratrol, BioPerine 
• Third-party testing: Yes

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Best Budget NMN Supplement

Genuine Purity Liposomal NMN+

Primary Rating:

3.5

Description:

• Daily dose: One capsule
• Cost per serving: Annual: $0.49 per serving / Semi-annual: $0.55 per serving / One-time purchase: $1.17 per serving
• NMN per serving: 250 milligrams
• Key ingredients: Nicotinamide mononucleotide
• Third-party testing: No

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Best Pure NMN Supplement

partiQlar Pure NMN

Primary Rating:

4.0

Description:

• Daily dose: One capsule
• Cost per serving: Annual: $0.71 per serving / Semi-annual: $0.90 per serving / One-time purchase: $1.20 per serving
• NMN per serving: 500 milligrams
• Key ingredients: Nicotinamide mononucleotide
• Third-party testing: Yes

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Best Anti-Aging NMN Supplement

Wonderfeel Youngr NMN

Primary Rating:

4.5

Description:

• Daily dose: Two capsules
• Cost per serving: Introductory monthly subscription: $2.43 per serving / Regular monthly subscription: $2.76 per serving / One-time purchase: $2.93 per serving
• NMN per serving: 900 milligrams
• Key ingredients: Nicotinamide mononucleotide, vitamin D3, trans-resveratrol, olive fruit extract, ergothioneine
• Third-party testing: Yes

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FAQs

Research

1. Rungratanawanich, W., Qu, Y., Wang, X. et al. Advanced glycation end products (AGEs) and other adducts in aging-related diseases and alcohol-mediated tissue injury. Exp Mol Med 53, 168–188 (2021). https://doi.org/10.1038/s12276-021-00561-7.
2. Liang Y, Xu X, Yin M, Zhang Y, Huang L, Chen R, Ni J. Effects of berberine on blood glucose in patients with type 2 diabetes mellitus: a systematic literature review and a meta-analysis. Endocr J. 2019 Jan 28;66(1):51-63. doi: 10.1507/endocrj.EJ18-0109. Epub 2018 Nov 3. PMID: 30393248.
3. Thondre, P.S., Lightowler, H., Ahlstrom, L. et al. Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomized, double blind, placebo-controlled study. Nutr Metab (Lond) 18, 41 (2021). https://doi.org/10.1186/s12986-021-00571-2.
4. Kiechl S, Pechlaner R, Willeit P, Notdurfter M, Paulweber B, Willeit K, Werner P, Ruckenstuhl C, Iglseder B, Weger S, Mairhofer B, Gartner M, Kedenko L, Chmelikova M, Stekovic S, Stuppner H, Oberhollenzer F, Kroemer G, Mayr M, Eisenberg T, Tilg H, Madeo F, Willeit J. Higher spermidine intake is linked to lower mortality: a prospective population-based study. Am J Clin Nutr. 2018 Aug 1;108(2):371-380. doi: 10.1093/ajcn/nqy102. PMID: 29955838.
5. Igarashi, M., Nakagawa-Nagahama, Y., Miura, M. et al. Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men. npj Aging 8, 5 (2022). https://doi.org/10.1038/s41514-022-00084-z.
6. Tomé-Carneiro J, Gonzálvez M, Larrosa M, Yáñez-Gascón MJ, García-Almagro FJ, Ruiz-Ros JA, García-Conesa MT, Tomás-Barberán FA, Espín JC. One-year consumption of a grape nutraceutical containing resveratrol improves the inflammatory and fibrinolytic status of patients in primary prevention of cardiovascular disease. Am J Cardiol. 2012 Aug 1;110(3):356-63. doi: 10.1016/j.amjcard.2012.03.030. Epub 2012 Apr 19. PMID: 22520621.
7. Zhu X, Wu C, Qiu S, Yuan X, Li L. Effects of resveratrol on glucose control and insulin sensitivity in subjects with type 2 diabetes: systematic review and meta-analysis. Nutr Metab (Lond). 2017 Sep 22;14:60. doi: 10.1186/s12986-017-0217-z. PMID: 29018489; PMCID: PMC5610395.
8. Baur JA, Sinclair DA. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov. 2006 Jun;5(6):493-506. doi: 10.1038/nrd2060. Epub 2006 May 26. PMID: 16732220.
9. Leonard SS, Xia C, Jiang BH, Stinefelt B, Klandorf H, Harris GK, Shi X. Resveratrol scavenges reactive oxygen species and effects radical-induced cellular responses. Biochem Biophys Res Commun. 2003 Oct 3;309(4):1017-26. doi: 10.1016/j.bbrc.2003.08.105. PMID: 13679076.
10. Jang JH, Surh YJ. Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death. Free Radic Biol Med. 2003 Apr 15;34(8):1100-10. doi: 10.1016/s0891-5849(03)00062-5. PMID: 12684095.
11. Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell. 2006 Dec 15;127(6):1109-22. doi: 10.1016/j.cell.2006.11.013. Epub 2006 Nov 16. PMID: 17112576.
12. Gopi S, Balakrishnan P. Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid (vitamin C) and their enhanced bioavailability. J Liposome Res. 2021 Dec;31(4):356-364. doi: 10.1080/08982104.2020.1820521. Epub 2020 Oct 6. PMID: 32901526.
13. “Quality.” partiQlar, 6 Jan. 2023, partiqlar.com/quality/.
14. Fantini C, Corinaldesi C, Lenzi A, Migliaccio S, Crescioli C. Vitamin D as a Shield against Aging. Int J Mol Sci. 2023 Feb 25;24(5):4546. doi: 10.3390/ijms24054546. PMID: 36901976; PMCID: PMC10002864.
15. Pilz S, Frisch S, Koertke H, Kuhn J, Dreier J, Obermayer-Pietsch B, Wehr E, Zittermann A. Effect of vitamin D supplementation on testosterone levels in men. Horm Metab Res. 2011 Mar;43(3):223-5. doi: 10.1055/s-0030-1269854. Epub 2010 Dec 10. PMID: 21154195.
16. D’Angelo C, Franceschelli S, Quiles JL, Speranza L. Wide Biological Role of Hydroxytyrosol: Possible Therapeutic and Preventive Properties in Cardiovascular Diseases. Cells. 2020 Aug 21;9(9):1932. doi: 10.3390/cells9091932. PMID: 32825589; PMCID: PMC7565717.
17. Paul BD. Ergothioneine: A Stress Vitamin with Antiaging, Vascular, and Neuroprotective Roles? Antioxid Redox Signal. 2022 Jun;36(16-18):1306-1317. doi: 10.1089/ars.2021.0043. Epub 2021 Dec 7. PMID: 34619979; PMCID: PMC9221166.
18. Shade C. The Science Behind NMN-A Stable, Reliable NAD+Activator and Anti-Aging Molecule. Integr Med (Encinitas). 2020 Feb;19(1):12-14. PMID: 32549859; PMCID: PMC7238909.
19. Mills KF, Yoshida S, Stein LR, Grozio A, Kubota S, Sasaki Y, Redpath P, Migaud ME, Apte RS, Uchida K, Yoshino J, Imai SI. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016 Dec 13;24(6):795-806. doi: 10.1016/j.cmet.2016.09.013. Epub 2016 Oct 27. PMID: 28068222; PMCID: PMC5668137.
20. Liao B, Zhao Y, Wang D, Zhang X, Hao X, Hu M. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. J Int Soc Sports Nutr. 2021 Jul 8;18(1):54. doi: 10.1186/s12970-021-00442-4. PMID: 34238308; PMCID: PMC8265078.
21. Tarantini S, Valcarcel-Ares MN, Toth P, Yabluchanskiy A, Tucsek Z, Kiss T, Hertelendy P, Kinter M, Ballabh P, Süle Z, Farkas E, Baur JA, Sinclair DA, Csiszar A, Ungvari Z. Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019 Jun;24:101192. doi: 10.1016/j.redox.2019.101192. Epub 2019 Apr 10. PMID: 31015147; PMCID: PMC6477631.

The post Best NMN Supplement: Fountain of Youth in a Bottle? (2024) appeared first on Breaking Muscle.

As a personal trainer and fitness nutrition specialist with over 20 years of experience, I’m often asked, “How do I naturally increase testosterone?” While strength training and balanced nutrition are fundamental for healthy testosterone levels, those seeking an additional lift can consider testosterone boosters. 

I tested seven testosterone boosters, each with different formulas and key ingredients. Here’s the thing — my testosterone levels were already above average. For me, this was a test to see which testosterone boosters could keep my levels where they were or even get them higher without the consequence of estrogen dominance (which can be a side effect of overconsuming testosterone boosters). Keep that in mind as I review my top picks for the best testosterone booster for men.

Medical disclaimer: This article is intended for educational and informational purposes only. It is not intended as a substitute for medical advice. For health advice, contact a licensed healthcare provider.

How We Chose the Best Testosterone Boosters

Navigating the saturated market of testosterone boosters can be a daunting task, especially when every product claims to be the best solution. 

To cut through the noise and offer genuine recommendations, we adopted a systematic approach grounded in science, transparency, and real-world feedback.

Here’s how we chose the best testosterone boosters for you:

Research-Backed Ingredients

We prioritized products that contain ingredients scientifically shown to enhance testosterone production or support hormonal balance. Ingredients like fenugreek, vitamin D, and zinc consistently surfaced as key compounds with the research and studies to back them up.

Safety Profile

No supplement is worth risking your health over. We stuck to the products that had tried-and-true ingredients, free of unnecessary fillers or harmful additives. Additionally, products with a history of causing side effects were immediately excluded from our list.

Customer Reviews and Testimonials

Real-world experiences from men who’ve tried these boosters provided unique insights. We looked over hundreds of user reviews, searching for consistent reports of efficacy, benefits, and any potential drawbacks.

Company Reputation

A company’s track record matters. We selected brands with a history of integrity, transparency, and commitment to customer satisfaction.

Value for Money

While price isn’t the only indicator of a product’s worth, we wanted to ensure that our top picks offer a good balance between cost and effectiveness. In other words, we wanted to select the products that offered the most bang for your buck.

Third-Party Testing

Supplements that have undergone third-party testing offer an additional layer of trustworthiness. We favored products that had been tested for purity and potency by independent labs.

Our Top Picks for the Best Testosterone Boosters

• Best Testosterone Booster Overall: TestoPrime
• Best Natural Testosterone Booster: XWERKS Ashwa
• Best Testosterone Booster for Muscle Growth: CrazyBulk Testo-Max
• Best Testosterone Booster for Men Over 50: PrimeGENIX Testodren
• Best Testosterone Booster for Burning Fat: Testosil
• Best Testosterone Booster for Bodybuilding: D-Bal MAX
• Best Anti-Aging Testosterone Booster: Lifeforce DHEA

Best Testosterone Booster Overall: TestoPrime

TestoPrime

4.5

• Daily dose: Four capsules
• Cost per serving: One bottle: $2.16 per serving / Three-bottle bundle: $1.44 per serving
• Key ingredients: D-aspartic acid, Panax ginseng, KSM 66® ashwagandha extract, and fenugreek
• Third-party testing: Yes

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TestoPrime stands out as the best testosterone booster overall due to its potent ingredients, user accessibility, and glowing reviews. Ideal for beginners, this booster strikes a harmonious balance; neither overwhelmingly potent nor disappointingly mild.

TestoPrime relies on several heavy hitter ingredients including: 

• D-aspartic acid (2,000 milligrams): A well-researched amino acid that can support the production of luteinizing hormone, which is responsible for testosterone production. (2)
• Fenugreek (equivalent to 800 milligrams): A popular herb in traditional medicine known for its potential to boost libido and testosterone levels. (3)
• Green tea extract (equivalent to 4,000 milligrams): A powerhouse antioxidant that might indirectly support testosterone levels by reducing the conversion of testosterone to DHT. (4)

It also includes a proper dose of vitamin D3 (26.68 micrograms) and zinc (40 milligrams) — both of which have been shown to support healthy testosterone levels. (5)(6)

While many of the products on this list share similar ingredients, for TestoPrime, D-aspartic acid takes center stage. Though its efficacy is debated, a 2009 study reported significant testosterone increases in both humans and rats after 12 days of consistent dosing. Another study linked D-aspartic acid supplementation to improved sperm quality in sub-fertile men. (7)(8)

Although some research finds negligible effects, the combination of D-aspartic acid and other potent ingredients in TestoPrime might amplify its impact.

I decided to take TestoPrime as a part of my pre-workout supplement routine, hoping to capitalize on its reported energy-boosting benefits. I took the four-capsule serving 30 to 60 minutes before my strength training workouts.

Whether it was the D-aspartic acid or Panax ginseng, I did feel an increase in energy, especially during my heavier sets. My sex drive, libido, and performance all stayed the same during the time I was taking TestoPrime — and that’s a good thing!

My biggest issues with TestoPrime are the absence of vitamin K2 and the low dose of ashwagandha. 

Vitamin K2 can significantly improve the absorption and utilization of vitamin D3, so it’s essential to pair the two. 

As for ashwagandha, the amount used in TestoPrime is less than 700 milligrams per serving. Compare that to XWERKS, which contains more than double that at 1.5 grams. Also, if you buy ashwagandha powder on its own, a teaspoon will provide you with three grams per serving, which is more than all of the supplements on this list.

If you choose TestoPrime, my advice would be to take it with a vitamin K2 supplement. I’d also advise mixing ashwagandha powder with your morning coffee or protein shake. That would make this a near-perfect testosterone booster.

Best Natural Testosterone Booster: XWERKS Ashwa

XWERKS Ashwa

4.0

• Daily dose: Two gummies
• Cost per serving: $0.63 per serving
• Key ingredients: Ashwagandha extract
• Third-party testing: No

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Ashwagandha is a tough-to-pronounce but highly effective ingredient for supporting hormone health. This single-ingredient supplement is ranked as the best natural testosterone booster because ashwagandha has been used for centuries to potentially reduce stress and enhance hormone health. Research is finally proving what many cultures have already known.

In fact, it’s one of the most studied and confirmed ingredients for promoting natural testosterone levels.

In one study, subjects taking ashwagandha over 16 weeks saw an 18 percent greater increase in DHEA-S (Dehydroepiandrosterone-sulfate) and a 14.7 percent greater increase in testosterone compared to the placebo group. (9)

DHEA-S is a hormone produced by your adrenal glands, and it’s important for two reasons: it’s seen as a marker for adrenal function, and it serves as a building block for testosterone. The increase of DHEA-S is important because, as a precursor, it directly supports the production of testosterone. (9)

In another eight-week study, men who consumed 600 milligrams of ashwagandha daily saw a 40 percent rise in their DISF‐M score, compared to a 25 percent rise in those given a placebo. The DISF-M is a questionnaire that consists of 25 questions, divided into five categories: 

• Sexual cognition/fantasy
• Sexual arousal
• Sexual behavior/experiences
• Orgasm
• Drive/desire

The men taking ashwagandha reported higher levels and events in each of the five categories, suggesting testosterone levels increased. (10)

Hands down, XWERKS Ashwa was my favorite supplement to take because it was like getting a chance to eat candy. The gummies tasted great, and the texture was just right. To ensure I had a consistent amount of ashwagandha in my system, I spaced out the serving, taking one gummy in the late morning and another just before bed.

I noticed my sleep improved when taking the ashwagandha before bed. This might have something to do with ashwagandha being a cortisol-reducing ingredient.

While I can’t attribute any wild gains in the gym to ashwagandha, I can say that I felt more level-headed even during times of stress. I also slept better, which is great for supporting growth hormone production.

My only problem with XWERKS Ashwa is that it doesn’t include black pepper extract, an ingredient that can enhance bioavailability. Easy fix: just buy Bioperine and take a serving whenever you use ashwagandha.

Best Testosterone Booster for Muscle Growth: CrazyBulk Testo-Max

CrazyBulk Testo-Max

4.2

• Daily dose: Four capsules
• Cost per serving: One bottle: $2.16 per serving / Three bottle bundle: $1.44 per serving
• Key ingredients: Vitamin D3, D-aspartic acid, nettle leaf extract, Korean red ginseng extract, and fenugreek 
• Third-party testing: No

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CrazyBulk Testo-Max is the best testosterone booster for muscle growth since it may support size gains in two important ways: increased performance in the gym and enhanced testosterone production.

Let’s talk about weight room performance. You can trigger muscle growth (hypertrophy) when you stress muscle tissue with intense training, causing a series of microtears. The actual growth happens during the recovery phase, but you need the energy and determination to tear down that muscle in the first place. 

With more energy in the gym, you’re better positioned to effectively hit the target muscles. Testo-Max, rich in ingredients like Korean red ginseng extract, can boost stamina, reduce fatigue, and sharpen focus. (11)

Once you’re out of the gym, growth hormones like testosterone step in to repair the muscle tissue, slowly building it back bigger and stronger after each workout.

Testo-Max contains many of the same testosterone-boosting ingredients discussed above, such as fenugreek, D-aspartic acid, and vitamin D. One unique ingredient is stinging nettle leaf extract. It’s known for boosting free (active) testosterone levels by binding to the testosterone-inhibiting molecule, sex hormone-binding globulin (SHBG). (12)

What’s more, Bioperine enhances the bioavailability of all ingredients in Testo-Max, ensuring you get maximum efficacy from the supplement. (13) 

The Bioperine is an excellent addition because other testosterone boosters, like XWERKS Ashwa, don’t have it. It’s one less supplement you have to worry about taking separately, which can be more cost-effective in the long run.

I appreciate Testo-Max as a non-stimulant pre-workout and as a testosterone booster. While not as potent as caffeine, it offers consistent focus during light sessions. For intense workouts, I stuck with my favorite pre-workout with stimulants.

My one gripe is with the Testo-Max marketing and the idea that this supplement can help you see visible results in two weeks. CrazyBulk made a reputation for itself by using clever names that sound a lot like performance-enhancing drugs. Make no mistake about it: Testo-Max is no steroid. Sure, you’ll probably see muscle growth while using Testo-Max, but it’ll take longer than two weeks.

RELATED: Best Mass Gainer

Best Testosterone Booster for Men Over 50: PrimeGENIX Testodren

PrimeGENIX Testodren

3.8

• Daily dose: One capsule
• Cost per serving: One bottle: $1.99 per serving / Three bottle bundle: $1.33 per serving
• Key ingredients: Furosap® 
• Third-party testing: Yes

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The average guy will lose an average of 1.6 percent of total testosterone each year once he gets to his mid-30s. (1) But what happens when you want to increase your testosterone levels in your 50s without a trip to the doctor?

Introducing PrimeGENIX Testodren, my pick for the best testosterone booster for men over 50.

Testodren contains a unique form of fenugreek, which may enhance libido, increase testosterone levels, and boost sexual performance.

In one study, men who consumed a 600-milligram fenugreek supplement daily for 12 weeks experienced elevated levels of both free and total testosterone. Additionally, these individuals reported enhanced sexual performance, marked by an increase in sexual activity frequency. (3)

As cited by the Testodren website, one of the main issues with many fenugreek supplements is inconsistent protodioscin levels.

Protodioscin is a natural compound found in fenugreek. It’s believed to help boost testosterone levels by stimulating the release of nitric oxide and increasing the activity of certain enzymes. With that said, researchers aren’t exactly sure how it works; however, protodioscin is the key to fenugreek’s testosterone-boosting benefits. 

To address the issue of inconsistent and low levels of protodioscin in most supplements, Testodren uses a patented purification technique that ensures a consistent protodioscin level of 20 percent in each serving — easily some of the highest levels in the industry.

This formula was tested in three human-based clinical trials and the results were impressive. In one study, older male subjects saw their free testosterone levels increase by 72.87 percent in 12 weeks. (14) 

If you’re a man in your 50s (or older) looking to naturally boost your testosterone levels, PrimeGENIX Testodren can be the way to go. Not only does it offer clinically proven results, but the brand is committed to purity and transparency with its third-party testing. Most of the supplements you’ll see online or on store shelves don’t bother with third-party testing, which is considered the gold standard by many experts. 

Put excellent customer service on top of that and you can see why it’s my pick for the best testosterone booster for men over 50.

Best Testosterone Booster for Burning Fat: Testosil

Testosil

4.0

• Daily dose: Four capsules
• Cost per serving: One bottle: $1.99 per serving / Three bottle bundle: $1.33 per serving
• Key ingredients: D-aspartic acid, KSM 66® ashwagandha extract, l-arginine HCl, Asian ginseng, and fenugreek
• Third-party testing: No

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For guys aiming to pack on lean muscle and shed excess fat, having optimal testosterone levels is crucial. 

A downfall of low testosterone is the undesired gain in fat mass and a corresponding reduction in muscle tissue. So, how do we simultaneously tackle the issue of diminished testosterone and prevent fat accumulation?

Enter Testosil, the best testosterone booster for burning fat.

When it comes to boosting your T-levels, Testosil relies primarily on a super-concentrated extract of ashwagandha. While the extract is only 300 milligrams per serving, it provides you with the equivalent of 3,600 milligrams per serving of ordinary ashwagandha powder.

As I discussed above, ashwagandha is a reliable testosterone booster. It’s accompanied in the Testosil formula by some other familiar proven ingredients, including D-aspartic acid and ZMA (zinc, magnesium, and vitamin B6). It also contains an extract that provides the equivalent of 800 milligrams of fenugreek!

Testosil has its testosterone bases covered, but what about fat-burning ingredients?

L-arginine and Panax ginseng combined in a supplement offer a potent duo for potential fat-burning and weight management benefits. 

L-arginine, a precursor to nitric oxide, promotes enhanced blood flow, which can lead to improved exercise performance and greater calorie burn. Additionally, its role in stimulating growth hormone release may enhance fat metabolism and support muscle mass, which in turn, boosts resting calorie burn. (15)

Panax ginseng is known for its energy-boosting properties, which can help inside and outside of the gym. It also helps stabilize blood sugar levels, potentially reducing fat storage. Some studies hint at its role in increasing thermogenesis, further amplifying calorie burn. (16)

Together, their synergistic effects may offer an efficient approach to weight management.

While I didn’t notice any heightened fat loss with Testosil, I did enjoy stabilized testosterone levels. Just like with a few of the other supplements, I got into the habit of taking it just before a workout, especially during heavy lifting days. Even when I took it on an empty stomach, Testosil didn’t cause any weird digestive issues.

The one issue I have with Testosil is the low dosage of L-arginine HCl. While it does have other fat-burning ingredients, I think it’s safe to say that the star ingredient would be L-arginine. The problem is that Testosil only provides 250 milligrams per serving, which is less than what several key studies used. For example, some studies dosed L-arginine as low as two grams and as high as 30 grams per day. Either way, 250 milligrams isn’t going to cut it.

If your goal is to boost testosterone while decreasing fat mass, the most important factors to get right are your diet and workout routine. If those are a mess, no testosterone or fat-burning supplement will help you. Once you have those on track, I’d recommend pairing Testosil with another fat burner. Even just a separate L-arginine supplement would do the trick.

RELATED: Best Supplements for Weight Loss

Best Testosterone Booster for Bodybuilding: D-Bal MAX

D-bal MAX

4.2

• Daily dose: Four capsules
• Cost per serving: One bottle: $2.33 per serving / Three bottle bundle: $1.48 per serving
• Key ingredients: KSM 66® ashwagandha extract, l-arginine HCl, Senactiv®, zinc, and magnesium
• Third-party testing: No

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Let me start by saying that while this is a great testosterone booster for bodybuilding, you shouldn’t expect to go from 90 pounds soaking wet to a 225-pound bodybuilding champion in one month. I like D-Bal MAX, but I also want to make sure I’m helping you set realistic expectations.

D-Bal MAX prioritizes muscle and connective tissue repair, creating an optimal environment for the body to flourish and testosterone levels to spike. Its emphasis on muscle recuperation and combating inflammation earns it my recommendation as the best testosterone booster for bodybuilding.

While I like the supplement, in truth, I have a love-hate relationship with the formula of D-Bal MAX. 

On one hand, it contains ingredients that support one another in both bioavailability and benefit, especially when it comes to muscle recovery and testosterone production. 

For example, D-Bal MAX contains zinc and copper, which is important because zinc can decrease the absorption of copper in your body. If you’re taking additional copper supplements, you don’t need to be concerned about zinc hindering its absorption since you already have an ample amount of copper.

Magnesium and vitamin C also have a synergistic relationship. For example, vitamin C can enhance the body’s ability to absorb magnesium from the digestive tract. On the other hand, magnesium can help improve the efficiency of some of the body’s processes that use vitamin C (such as wound healing). When taken together, they can boost each other’s benefits in the body.

On the other hand, the formula contains the oxide forms of zinc and magnesium, which have the lowest bioavailability. I would love to see zinc picolinate or zinc citrate on the label — really anything but zinc oxide.

That aside, D-Bal MAX is an excellent muscle recovery agent that also offers testosterone support. Since it contains 200 milligrams of caffeine, I used it as a pre-workout supplement, taking it around 30 minutes before my gym session. That amount of caffeine with the added ginseng provided the boost I needed to get through serious sets. (17)

Be careful with your consumption of caffeine as it might impact your testosterone levels for better or worse. The right dosage in certain situations — mainly before exercise — may temporarily boost T levels. However, one study found that excessive caffeine consumption of more than 400 milligrams might lower testosterone levels because of high cortisol levels. (18) In other words, go easy on the cup of Joe.

Since the ingredients in D-Bal MAX all support some form of muscle repair, from anti-inflammatory properties to growth hormone secretion to improved glucose uptake, I also took it pre-workout to kickstart my recovery.

Better sets and recovery led to better results for me. I noticed my plate numbers steadily increasing from week to week, and people kept mentioning that my thighs and shoulders looked thicker. Full disclosure here: I was also taking creatine and glutamine, supplement staples that I’ve taken for most of my fitness career.

RELATED: Best Bodybuilding Supplements

Best Anti-Aging Testosterone Booster: Lifeforce DHEA

Lifeforce DHEA

4.0

• Daily dose: Three capsules
• Cost per serving: One-time order: $1.83 per serving / Subscribe and save: $1.16 per serving
• Key ingredients: DHEA, 7-Keto DHEA, and Pregnenolone
• Third-party testing: No

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Lifeforce DHEA incorporates three of the most studied and proven longevity ingredients: DHEA, pregnenolone, and 7-Keto DHEA. That’s why it got my vote as the best anti-aging testosterone booster.

What’s the connection between longevity, testosterone, and DHEA (Dehydroepiandrosterone)?

Just like testosterone, DHEA levels begin to steadily decline in men once they reach their mid-30s. Studies show that there is a direct correlation between lower levels of testosterone and DHEA and a worse state of general health. (19) 

Put simply: If you want to look and feel your best – like a younger version of yourself – you want to keep these levels in check. And that’s where Lifeforce DHEA comes in. Let’s break down these three important ingredients:

• DHEA is a hormone produced by the adrenal glands. It acts as a precursor to both testosterone and estrogen, which means it may increase testosterone levels, especially in older individuals whose natural DHEA levels have dwindled. (20)
• Pregnenolone is a steroid hormone but don’t let the name scare you! It’s not an illegal anabolic steroid. It’s a naturally occurring compound in your body from which other steroid hormones, including DHEA, progesterone, and testosterone, are derived. Some experts also believe that pregnenolone may promote other anti-aging benefits, including improved memory, alleviated stress, and elevated mood. (21)
• 7-Keto DHEA is a DHEA metabolite. While it does not directly boost testosterone levels, it does possess several anti-aging benefits. It may enhance metabolism, aid in weight loss, and support immune function. (22)

The most noticeable benefit from Lifeforce DHEA was the boost in energy that I had when I took it in the morning. I didn’t even bother with my usual cup of coffee until the early afternoon and that was more out of habit than actually needing it. I felt like that energy carried over into the gym because I was really focused on what I was doing as I moved between exercises.

My testosterone levels continued to soar high as I took Lifeforce DHEA, and this was evident by the uptick in libido and sex drive. Overall, I’d say it did an awesome job at helping me maintain my T-levels while giving me the added benefit of a cognitive boost.

RELATED: Best Multivitamin for Men

Additional Testosterone Booster Recommendations

On that note about Lifeforce DHEA, I’d like to highlight a unique service they offer, which isn’t provided by any other brand on this list.

Lifeforce offers an at-home health test that checks over 40 biomarkers in your body that impact your hormone levels, well-being, and generally how you feel every day. Of those 40 markers, Lifeforce checks your levels for luteinizing hormone and testosterone, the two things you want to increase (and the reason you’re reading this article).

Here’s how it works. You take the test at home, send it in, and you’ll receive a complete report with your results in about 10 days. But you’re not left on your own to interrupt those results. You’ll hop on a virtual call with a doctor to discuss things like your hormones, metabolism, organ health, and any health risks you might have. You’ll also receive a personalized health plan.

If you really want to go the extra mile and track your testosterone levels as you take one of these supplements, Lifeforce Diagnostic could be something to look into.

Learn more about what is provided in a Lifeforce membership on their website: Lifeforce Diagnostic Blood Test and save $225 on your initial diagnostic by using the code BREAKINGMUSCLE.

What Are the Benefits of Testosterone Boosters?

Before we dive into the benefits, it’s important to understand that taking a testosterone booster alone may not yield the transformational results you want.

A testosterone booster should be treated as a complement to a consistent resistance training program and a healthy, well-balanced diet. 

Put simply: For a testosterone booster to have the maximum effect, and for you to see the following benefits, you need to lift weights and eat a proper diet consisting of lean proteins, complex carbs, fruits, vegetables, and healthy fats. 

Furthermore, regardless of these potential benefits, it’s important to approach testosterone boosters with caution and knowledge. Results will vary from person to person. Always consider potential side effects and consult a healthcare professional before starting supplements.

Increased Testosterone Levels

Elevated testosterone can amplify various physiological functions, from improved muscle growth to enhanced mood and energy. 

I mention this first because the boost in your testosterone levels plays a direct role in making the other benefits on this list happen.

Improved Muscle Mass and Strength

One of the most cited advantages of increasing testosterone levels is the potential for greater muscle growth and strength. 

Testosterone plays a crucial role in muscle development, so it’s no surprise that many supplement users report improved muscle gains when combining these supplements with hypertrophy-focused resistance training.

Enhanced Libido

A decline in testosterone is often linked with a decrease in libido or sexual desire. 

Testosterone boosters can reignite that spark and improve sexual drive. Again, the best results happen when you’re using a testosterone booster in conjunction with a strength training program and a healthy diet.

Mood Enhancement

Testosterone has been linked with mood and mental well-being. Men with lower testosterone levels sometimes experience mood swings, depression, or irritability. 

Boosting levels might help alleviate these symptoms and promote a better overall mood.

Improved Energy Levels

Feeling constantly fatigued? Testosterone boosters might offer a solution. 

Users often report an increase in their energy levels, helping them feel more vibrant while reducing feelings of lethargy.

Enhanced Cognitive Function

Some studies suggest that optimal testosterone levels can help in maintaining cognitive health, including memory and focus. 

While more research is needed, some users claim to experience improved mental clarity after using these supplements.

Fat Loss

Elevated testosterone levels can help increase metabolism, which might assist in fat loss. 

While it’s not a replacement for a balanced diet and regular exercise, a testosterone booster could potentially play a role in a comprehensive weight loss strategy.

Bone Density

Testosterone plays a role in bone density. As men age and testosterone levels drop, there’s a potential risk of developing osteoporosis. Boosting testosterone might help in maintaining bone strength.

Improved Recovery

Athletes and fitness enthusiasts alike might find that testosterone boosters help them recover faster post-workout, thanks to the hormone’s role in muscle repair and regeneration.

What To Consider When Looking for a Testosterone Booster

How can you walk into your local supplement shop or browse an online supplement catalog and not feel overwhelmed by the choices?

There are literally dozens of options to choose from, and if you don’t know what you’re looking for, you might throw in the towel before clicking the “buy” button. 

Let’s take the stress out of the shopping experience. Here’s what to look for when buying a testosterone booster.

Your Goals

Before diving into the specifics of a product, identify what you hope to achieve. 

Are you looking for improved muscle mass, enhanced libido, mood elevation, or perhaps a combination of benefits? 

Understanding your goals will help you choose a booster that’s aligned with your needs.

Recommended Dosage

Different supplements have varied recommended dosages, and too many of them under-dose their products. At the same time, be careful of over-dosed supplements!

Overconsumption can lead to potential side effects such as acne, excessive estrogen levels, and generally feeling ill, while underconsumption might not yield the desired results.

A quick Google search can help you understand how much of a certain ingredient you should be taking to see results.

Ingredients

Pay close attention to the ingredients listed on the label. Look for products that contain clinically researched and proven ingredients such as the following:

• DHEA
• Fenugreek
• D-Aspartic Acid
• Ashwagandha
• Vitamin D3 (preferably with Vitamin K2)
• Zinc
• Magnesium
• Stinging Nettle Leaf

I recommend avoiding supplements with proprietary blends where the exact amounts of ingredients aren’t specified.

Safety

Always opt for products that are manufactured in facilities following Good Manufacturing Practices (GMP). 

Additionally, products that have been third-party tested for purity and potency are more likely to be trustworthy.

Two of the most trusted names in supplement third-party testing are NSF International and ConsumerLab. These organizations independently test and verify the contents of supplements, ensuring that what’s on the label matches what’s in the bottle and that harmful contaminants are not present.

PCT Requirements

Post Cycle Therapy (PCT) refers to supplements (or certain drugs) that are taken after a cycle of anabolic steroids or performance-enhancing compounds to help restore hormonal balance. It mainly focuses on kick-starting the production of natural testosterone and preventing estrogen-related side effects such as gynecomastia. Some of the most common PCTs include Clomid and Nolvadex.

If you want to avoid a mess of trouble, including throwing your hormones out of whack and possibly developing man boobs, I’d highly recommend staying away from any testosterone booster that requires a PCT supplement. Typically, natural testosterone boosters like the ones on this list will not require any type of “follow-up supplement” to avoid side effects. You should be able to start and stop taking the supplement without worrying about potential downsides.

Potential Side Effects

While testosterone boosters can offer numerous benefits, they may also come with potential side effects. Some common ones include acne, hair loss, or an increase in aggression. 

It’s essential to familiarize yourself with the possible side effects of any supplement you’re considering.

How To Boost Testosterone Naturally

While supplements can be an effective way to enhance testosterone levels, there are also several natural methods to boost this vital hormone. 

A holistic approach encompassing lifestyle changes and habits can play a fundamental role in optimizing your testosterone levels.

Diet and Nutrition

It’s easy to say, “Eat healthy,” but what does that mean in the context of increasing your testosterone levels? Here are some dietary tips that will support those T-levels.

• Get adequate amounts of zinc and vitamin D. These two nutrients are essential for testosterone production. Foods like oysters, beef, pumpkin seeds, and spinach are high in zinc, while fatty fish, fortified dairy products, and egg yolks are good sources of Vitamin D.
• Consume healthy fats. Don’t skip on the healthy fats! You can find monounsaturated and omega-3 fats in avocados, nuts, seeds, and fatty fish like salmon.
• Limit sugar and processed foods. High sugar consumption and a diet rich in processed foods can lead to insulin resistance, which may reduce testosterone levels.
• Limit alcohol and drugs. Excessive alcohol consumption can lower testosterone levels.

Regular Exercise

Any form of physical activity is good for healthy weight management, but if your goal is to boost your testosterone, you want to focus on two specific forms of exercise:

• Resistance training. Strength training or weightlifting has been shown to boost testosterone levels both immediately after a workout and over the long term. Aim for three days per week of some form of resistance training.
• High-intensity interval training (HIIT). Short, intense bursts of exercise like sprints or a HIIT workout can be effective for weight management, muscle growth, and testosterone production.

Lifestyle Choices

Outside of diet, exercise, and supplements, there are some changes you can make in your day-to-day routine to support healthy testosterone levels.

• Manage stress. Chronic stress elevates cortisol, a hormone that can lower testosterone. Techniques like meditation, deep breathing exercises, and regular physical activity can help manage and reduce stress.
• Get adequate sleep. Testosterone production follows a circadian rhythm, with peak production occurring during sleep. Aim for seven to nine hours of quality sleep per night to support optimal testosterone levels.
• Maintain a healthy weight. Obesity can negatively affect testosterone levels. Achieving and maintaining a healthy weight through diet and exercise can support optimal testosterone production.
• Avoid endocrine disruptors. Chemicals such as BPA, commonly found in some plastics, can act as endocrine disruptors, affecting testosterone levels. Choose BPA-free products and reduce exposure to potential environmental toxins. (23)
• Stay socially active. Engaging in social activities, bonding with friends and family, and maintaining healthy relationships can positively influence testosterone levels, especially as you age.
• Talk to your doctor if you take prescription medications. Certain medications can impact testosterone production, so it’s essential to discuss any concerns with your healthcare provider.

Final Thoughts

While TRT (testosterone replacement therapy) is a surefire way to increase testosterone levels, it’s also looked at as a last resort option. If you want to naturally increase your testosterone levels and fight back against the symptoms of low T, a testosterone booster supplement might be able to help.

Before getting drawn into the idea of testosterone boosters, remember the basics: working out and eating right. A testosterone booster should always act as a complement to well-established healthy lifestyle choices and habits. Once you’ve got those down, then think about adding a supplement.

Best Testosterone Boosters: Side-by-Side Comparison

Best Testosterone Booster Overall	Best Natural Testosterone Booster	Best Testosterone Booster for Muscle Growth	Best Testosterone Booster for Men Over 50	Best Testosterone Booster for Burning Fat	Best Testosterone Booster for Bodybuilding	Best Anti-Aging Testosterone Booster
TestoPrime	XWERKS Ashwa	CrazyBulk Testo-Max	PrimeGENIX Testodren	Testosil	D-bal MAX	Lifeforce DHEA
Primary Rating: 4.5	Primary Rating: 4.0	Primary Rating: 4.2	Primary Rating: 3.8	Primary Rating: 4.0	Primary Rating: 4.2	Primary Rating: 4.0
Description: Daily dose: Four capsules Cost per serving: One bottle: $2.16 per serving / Three-bottle bundle: $1.44 per serving Key ingredients: D-aspartic acid, Panax ginseng, KSM 66® ashwagandha extract, and fenugreek Third-party testing: Yes	Description: Daily dose: Two gummies Cost per serving: $0.63 per serving Key ingredients: Ashwagandha extract Third-party testing: No	Description: Daily dose: Four capsules Cost per serving: One bottle: $2.16 per serving / Three bottle bundle: $1.44 per serving Key ingredients: Vitamin D3, D-aspartic acid, nettle leaf extract, Korean red ginseng extract, and fenugreek  Third-party testing: No	Description: Daily dose: One capsule Cost per serving: One bottle: $1.99 per serving / Three bottle bundle: $1.33 per serving Key ingredients: Furosap®  Third-party testing: Yes	Description: Daily dose: Four capsules Cost per serving: One bottle: $1.99 per serving / Three bottle bundle: $1.33 per serving Key ingredients: D-aspartic acid, KSM 66® ashwagandha extract, l-arginine HCl, Asian ginseng, and fenugreek Third-party testing: No	Description: Daily dose: Four capsules Cost per serving: One bottle: $2.33 per serving / Three bottle bundle: $1.48 per serving Key ingredients: KSM 66® ashwagandha extract, l-arginine HCl, Senactiv®, zinc, and magnesium Third-party testing: No	Description: Daily dose: Three capsules Cost per serving: One-time order: $1.83 per serving / Subscribe and save: $1.16 per serving Key ingredients: DHEA, 7-Keto DHEA, and Pregnenolone Third-party testing: No
Check Price	Check Price	Check Price	Check Price	Check Price	Check Price	Check Price

Best Testosterone Booster
Overall

TestoPrime

Primary Rating:

4.5

Description:

• Daily dose: Four capsules
• Cost per serving: One bottle: $2.16 per serving / Three-bottle bundle: $1.44 per serving
• Key ingredients: D-aspartic acid, Panax ginseng, KSM 66® ashwagandha extract, and fenugreek
• Third-party testing: Yes

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Best Natural
Testosterone
Booster

XWERKS Ashwa

Primary Rating:

4.0

Description:

• Daily dose: Two gummies
• Cost per serving: $0.63 per serving
• Key ingredients: Ashwagandha extract
• Third-party testing: No

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Best Testosterone Booster for Muscle Growth

CrazyBulk Testo-Max

Primary Rating:

4.2

Description:

• Daily dose: Four capsules
• Cost per serving: One bottle: $2.16 per serving / Three bottle bundle: $1.44 per serving
• Key ingredients: Vitamin D3, D-aspartic acid, nettle leaf extract, Korean red ginseng extract, and fenugreek 
• Third-party testing: No

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Best Testosterone Booster
for Men Over 50

PrimeGENIX Testodren

Primary Rating:

3.8

Description:

• Daily dose: One capsule
• Cost per serving: One bottle: $1.99 per serving / Three bottle bundle: $1.33 per serving
• Key ingredients: Furosap® 
• Third-party testing: Yes

Check Price

Best Testosterone Booster
for Burning Fat

Testosil

Primary Rating:

4.0

Description:

• Daily dose: Four capsules
• Cost per serving: One bottle: $1.99 per serving / Three bottle bundle: $1.33 per serving
• Key ingredients: D-aspartic acid, KSM 66® ashwagandha extract, l-arginine HCl, Asian ginseng, and fenugreek
• Third-party testing: No

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Best Testosterone Booster for Bodybuilding

D-bal MAX

Primary Rating:

4.2

Description:

• Daily dose: Four capsules
• Cost per serving: One bottle: $2.33 per serving / Three bottle bundle: $1.48 per serving
• Key ingredients: KSM 66® ashwagandha extract, l-arginine HCl, Senactiv®, zinc, and magnesium
• Third-party testing: No

Check Price

Best Anti-Aging Testosterone
Booster

Lifeforce DHEA

Primary Rating:

4.0

Description:

• Daily dose: Three capsules
• Cost per serving: One-time order: $1.83 per serving / Subscribe and save: $1.16 per serving
• Key ingredients: DHEA, 7-Keto DHEA, and Pregnenolone
• Third-party testing: No

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FAQs

Research

1. Stanworth RD, Jones TH. Testosterone for the aging male; current evidence and recommended practice. Clin Interv Aging. 2008;3(1):25-44. doi: 10.2147/cia.s190. PMID: 18488876; PMCID: PMC2544367.
2. Topo E, Soricelli A, D’Aniello A, Ronsini S, D’Aniello G. The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats. Reprod Biol Endocrinol. 2009 Oct 27;7:120. doi: 10.1186/1477-7827-7-120. PMID: 19860889; PMCID: PMC2774316.
3. Rao A, Steels E, Inder WJ, Abraham S, Vitetta L. Testofen, a specialised Trigonella foenum-graecum seed extract reduces age-related symptoms of androgen decrease, increases testosterone levels and improves sexual function in healthy aging males in a double-blind randomised clinical study. Aging Male. 2016 Jun;19(2):134-42. doi: 10.3109/13685538.2015.1135323. Epub 2016 Jan 20. PMID: 26791805.
4. Shin S, Kim K, Lee MJ, Lee J, Choi S, Kim KS, Ko JM, Han H, Kim SY, Youn HJ, Ahn KJ, An IS, An S, Cha HJ. Epigallocatechin Gallate-Mediated Alteration of the MicroRNA Expression Profile in 5α-Dihydrotestosterone-Treated Human Dermal Papilla Cells. Ann Dermatol. 2016 Jun;28(3):327-34. doi: 10.5021/ad.2016.28.3.327. Epub 2016 May 25. PMID: 27274631; PMCID: PMC4884709.
5. Pilz S, Frisch S, Koertke H, Kuhn J, Dreier J, Obermayer-Pietsch B, Wehr E, Zittermann A. Effect of vitamin D supplementation on testosterone levels in men. Horm Metab Res. 2011 Mar;43(3):223-5. doi: 10.1055/s-0030-1269854. Epub 2010 Dec 10. PMID: 21154195.
6. Te L, Liu J, Ma J, Wang S. Correlation between serum zinc and testosterone: A systematic review. J Trace Elem Med Biol. 2023 Mar;76:127124. doi: 10.1016/j.jtemb.2022.127124. Epub 2022 Dec 23. PMID: 36577241.
7. Topo, E., Soricelli, A., D’Aniello, A. et al. The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats. Reprod Biol Endocrinol 7, 120 (2009). https://doi.org/10.1186/1477-7827-7-120.
8. G. D’Aniello, S. Ronsini, T. Notari, N. Grieco, V. Infante, N. D’Angel, F. Mascia, M. Fiore, G. Fisher and A. D’Aniello, “D-Aspartate, a Key Element for the Improvement of Sperm Quality,” Advances in Sexual Medicine, Vol. 2 No. 4, 2012, pp. 45-53. doi: 10.4236/asm.2012.24008.
9. Lopresti AL, Drummond PD, Smith SJ. A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha (Withania somnifera) in Aging, Overweight Males. American Journal of Men’s Health. 2019;13(2). doi:10.1177/1557988319835985
10. Chauhan S, Srivastava MK, Pathak AK. Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: A randomized controlled trial. Health Sci Rep. 2022 Jul 20;5(4):e741. doi: 10.1002/hsr2.741. PMID: 35873404; PMCID: PMC9297375.
11. Yeo HB, Yoon HK, Lee HJ, Kang SG, Jung KY, Kim L. Effects of Korean Red Ginseng on Cognitive and Motor Function: A Double-blind, Randomized, Placebo-controlled Trial. J Ginseng Res. 2012 Apr;36(2):190-7. doi: 10.5142/jgr.2012.36.2.190. PMID: 23717119; PMCID: PMC3659585.
12. Chrubasik JE, Roufogalis BD, Wagner H, Chrubasik S. A comprehensive review on the stinging nettle effect and efficacy profiles. Part II: urticae radix. Phytomedicine. 2007 Aug;14(7-8):568-79. doi: 10.1016/j.phymed.2007.03.014. Epub 2007 May 16. PMID: 17509841.
13. Kesarwani K, Gupta R, Mukerjee A. Bioavailability enhancers of herbal origin: an overview. Asian Pac J Trop Biomed. 2013 Apr;3(4):253-66. doi: 10.1016/S2221-1691(13)60060-X. PMID: 23620848; PMCID: PMC3634921.
14. Maheshwari A, Verma N, Swaroop A, Bagchi M, Preuss HG, Tiwari K, Bagchi D. Efficacy of Furosap^TM, a novel Trigonella foenum-graecum seed extract, in Enhancing Testosterone Level and Improving Sperm Profile in Male Volunteers. Int J Med Sci. 2017 Jan 10;14(1):58-66. doi: 10.7150/ijms.17256. PMID: 28138310; PMCID: PMC5278660.
15. Oh HS, Oh SK, Lee JS, Wu C, Lee SJ. Effects of l-arginine on growth hormone and insulin-like growth factor 1. Food Sci Biotechnol. 2017 Dec 12;26(6):1749-1754. doi: 10.1007/s10068-017-0236-6. PMID: 30263714; PMCID: PMC6049717.
16. Amerikanou, Charalampia & Kaliora, Andriana & Gioxari, Aristea. (2021). The efficacy of Panax ginseng in obesity and the related metabolic disorders. Pharmacological Research – Modern Chinese Medicine. 1. 100013. 10.1016/j.prmcm.2021.100013.
17. Alsunni AA. Energy Drink Consumption: Beneficial and Adverse Health Effects. Int J Health Sci (Qassim). 2015 Oct;9(4):468-74. PMID: 26715927; PMCID: PMC4682602.
18. Glover, F.E., Caudle, W.M., Del Giudice, F. et al. The association between caffeine intake and testosterone: NHANES 2013–2014. Nutr J 21, 33 (2022). https://doi.org/10.1186/s12937-022-00783-z.
19. Walther A, Seuffert J. Testosterone and Dehydroepiandrosterone Treatment in Ageing Men: Are We All Set? World J Mens Health. 2020 Apr;38(2):178-190. doi: 10.5534/wjmh.190006. Epub 2019 Jun 4. PMID: 31190486; PMCID: PMC7076306.
20. Li Y, Ren J, Li N, Liu J, Tan SC, Low TY, Ma Z. A dose-response and meta-analysis of dehydroepiandrosterone (DHEA) supplementation on testosterone levels: perinatal prediction of randomized clinical trials. Exp Gerontol. 2020 Nov;141:111110. doi: 10.1016/j.exger.2020.111110. Epub 2020 Oct 10. PMID: 33045358.
21. Ramírez S, Haddad-Tóvolli R, Radosevic M, Toledo M, Pané A, Alcolea D, Ribas V, Milà-Guasch M, Pozo M, Obri A, Eyre E, Gómez-Valadés AG, Chivite I, Van Eeckhout T, Zalachoras I, Altirriba J, Bauder C, Imbernón M, Garrabou G, Garcia-Ruiz C, Nogueiras R, Soto D, Gasull X, Sandi C, Brüning JC, Fortea J, Jiménez A, Fernández-Checa JC, Claret M. Hypothalamic pregnenolone mediates recognition memory in the context of metabolic disorders. Cell Metab. 2022 Feb 1;34(2):269-284.e9. doi: 10.1016/j.cmet.2021.12.023. PMID: 35108514; PMCID: PMC8815774.
22. Kalman, Douglas & Colker, Carlon & Swain, Melissa & Torina, Georgeann & Shi, Qingwei. (2000). A randomized, double-blind, placebo-controlled study of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy overweight adults. Current Therapeutic Research-clinical and Experimental – CURR THER RES. 61. 435-442. 10.1016/S0011-393X(00)80026-0.
23. Cariati, F., D’Uonno, N., Borrillo, F. et al. “Bisphenol a: an emerging threat to male fertility”. Reprod Biol Endocrinol 17, 6 (2019). https://doi.org/10.1186/s12958-018-0447-6.

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